Chen et al. - BMJ Med (2024)
Chen et al. - BMJ Med (2024)
TL;Dr.: In a study published in BMJ Medicine, Chen and colleagues investigated the effects of fish oil supplements on cardiovascular disease progression. The prospective cohort study involved 415,737 participants aged 40 to 69 from the UK Biobank, and the median follow-up was 11.9 years. Results indicated that regular fish oil use may increase risks of atrial fibrillation and stroke in healthy individuals (hazard ratios, 1.13 and 1.05, respectively). However, in participants with a cardiovascular disease diagnosis, regular fish oil use was associated with a beneficial impact on the transition of atrial fibrillation to major adverse cardiovascular events (HR, 0.92) and myocardial infarction (HR, 0.85) and of heart failure to death (HR, 0.91). These findings suggest a dual role of fish oil in cardiovascular progression, highlighting the need for targeted guidance on its use.